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Antibody mediated lysis of hapten-conjugated target cells by macrophages and by complement: The influence of IgG subclass, antibody and hapten density

✍ Scribed by Kata Miklós; Máté Tolnay; Hervé Bazin; György A. Medgyesi


Book ID
118384483
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
759 KB
Volume
29
Category
Article
ISSN
0161-5890

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Effect of prior sensitization with hapte
✍ S. H. Leech; N. A. Mitchison 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

## Abstract Mice tolerized by low doses of bovine IgG (BGG), immunized with arsanilated (ARS) conjugates and challenged with ARS‐BGG show an augmented anti‐ BGG antibody response compared with controls immunized with nonconjugated carrier. Conditions optimal for generating hapten help are explored