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Antibody mediated class I signal transduction in human endothelial cells is regulated by the degree of molecular aggregation

✍ Scribed by Yi-Ping Jin; Michael S. Bennett; Dennis J. Montoya; Kelsey N. Retting; Elaine F. Reed

Book ID
116530453
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
29 KB
Volume
65
Category
Article
ISSN
0198-8859

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## Abstract Allografts transplanted across HLA‐sensitization results in an antibody‐mediated rejection known as hyperacute rejection. Depleting anti‐graft antibodies from the recipient by plasmapheresis prior to transplantation can prevent this rejection. We developed an __in vitro__ model using po