Antibody-Induced Failure of Botulinum Toxin A Therapy in Cosmetic Indications
β Scribed by DIRK DRESSLER; KAI WOHLFAHRT; ELLEN MEYER-ROGGE; LUITGARD WIEST; HANS BIGALKE
- Book ID
- 109077086
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 792 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1076-0512
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π SIMILAR VOLUMES
Therapy with botulinum toxin (BT) can fail due to numerous reasons, including failure due to formation of antibodies against BT (BT-AB, AB-TF). AB-TF is a secondary therapy failure, i.e. it occurs during the course of an ongoing BT therapy. It can be subjective or objective, temporary or permanent,
## Abstract In some patients, therapy with botulinum toxin type A (BTβA) becomes ineffective due to formation of antibodies (BTβAβAB). The time course of BTβAβAB titres after cessation of BTβA therapy was quantitatively studied to determine whether and when they might drop. Thirteen patients (eight