๐”– Bobbio Scriptorium
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Antibody Engineering Volume c || Chimeric Antigen Receptors for T-Cell Based Therapy

โœ Scribed by Chames, Patrick


Book ID
115444735
Publisher
Humana Press
Year
2012
Weight
263 KB
Category
Article
ISBN
1617799742

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## Anti -CD3 ุ‹ anti-B-cell antigen bispecific monoclonal antibodies (bsAbs) can redirect T-cell-mediated lysis toward malignant B cells. Clinical trials with CD3-based bsAbs have shown toxicity in patients which is likely related to nonspecific T-cell activation and targeting. Our current studies