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Antibody-dependent cell-mediated cytotoxicity for cultured autologous melanoma cells

✍ Scribed by Philip O. Livingston; Richard Michitsch; Hiroshi Shiku; Carl M. Pinsky; Herbert F. Oettgen


Book ID
115812576
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
802 KB
Volume
64
Category
Article
ISSN
0008-8749

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Cell-mediated cytotoxicity for cultured
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## Abstract Peripheral blood lymphocytes from 32 patients with malignant melanoma were tested for cell‐mediated cytotoxicity (CMC) against cultured autologous melanoma cells. Effector cells were prepared from venous blood by defibrination, gel sedimentation, nylon column filtration, and lysis of re

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## Abstract A sensitive assay for antibody‐dependent cell‐mediated cytotoxicity (ADCMC) was developed utilizing serum from a patient with gestational choriocarcinoma and the ^3^H‐proline microcytotoxicity test for detection of destruction of monolayer target cells. Conditions for optimal expression