## Abstract Peripheral blood lymphocytes from 32 patients with malignant melanoma were tested for cellβmediated cytotoxicity (CMC) against cultured autologous melanoma cells. Effector cells were prepared from venous blood by defibrination, gel sedimentation, nylon column filtration, and lysis of re
β¦ LIBER β¦
Antibody-dependent cell-mediated cytotoxicity for cultured autologous melanoma cells
β Scribed by Philip O. Livingston; Richard Michitsch; Hiroshi Shiku; Carl M. Pinsky; Herbert F. Oettgen
- Book ID
- 115812576
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 802 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0008-8749
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## Abstract A sensitive assay for antibodyβdependent cellβmediated cytotoxicity (ADCMC) was developed utilizing serum from a patient with gestational choriocarcinoma and the ^3^Hβproline microcytotoxicity test for detection of destruction of monolayer target cells. Conditions for optimal expression