✦ LIBER ✦

Antibody-dependent cell-mediated cytotoxicity against epstein-barr virus membrane antigen in african Burkitt's lymphoma

✍ Scribed by David J. Granlund; Francis Nkrumah; I. Virginia Perkins; Robert J. Biggar; Paul H. Levine; David A. Fuccillo

Publisher: John Wiley and Sons
Year: 1979
Tongue: French
Weight: 366 KB
Volume: 24
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910240508

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Serial samples of sera from patients with African Burkitt's lymphoma were tested for antibody against Epstein‐Barr virus (EBV)‐specific membrane antigen (MA) by the antibody‐dependent cell‐mediated cytotoxicity assay (ADCC). Titers of patients in the long‐term survivor group were generally higher than those found in the sera of patients in the short‐term survivor group. Although ADCC titers to EBV‐MA were not useful in predicting which patients would relapse there was a definite relationship between ADCC titer and prognosis. The individual differences in ADCC titers in patients in remission may explain the variability of responses that have been reported in studies on serotherapy with remission plasma.

📜 SIMILAR VOLUMES

Relationship between clinical stage, his

Relationship between clinical stage, histopathology and antibody titers against the second epstein-barr virus nuclear antigen (EBNA-2) in non-Hodgkin's lymphoma patients

✍ G. Masucci; H. Mellstedt; G. Henle; W. Henle; L. Rymo; M. G. Masucci; I. Ernberg 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 492 KB 👁 1 views

6To whom reprint requests should be sent.

Retinoic acid induces persistent, RARα-m

Retinoic acid induces persistent, RARα-mediated anti-proliferative responses in Epstein-Barr virus–immortalized b lymphoblasts carrying an activated c-myc oncogene but not in Burkitt's lymphoma cell lines

✍ Roberta Cariati; Paola Zancai; Michele Quaia; Giovanna Cutrona; Franca Giannini; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 260 KB 👁 1 views

We have previously demonstrated that 13-cis-retinoic acid (RA), 9-cis-RA and all-trans-RA (ATRA) powerfully inhibit the proliferation of Epstein-Barr virus-immortalized B-lymphoblastoid cell lines (LCLs). The aim of the present study was to assess whether these compounds are effective at inhibiting