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Antibody-Catalyzed Enantioselective Norrish Type II Cyclization

✍ Scribed by Sigal Saphier; Subhash C. Sinha; Ehud Keinan


Book ID
101528474
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
90 KB
Volume
115
Category
Article
ISSN
0044-8249

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In contary to the general notion that b-arylpropiophenones are photostable, photolysis of b-anisylketones 1 and 2 is found to result in Norrish Type II reactions; Yang cyclization affords two cyclobutanols in moderate yields (31-43%) in a highly stereoselective manner. The solvents are found to exer