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Antibody arrays identify protein-protein interactions in chronic myeloid leukaemia

โœ Scribed by Hetal Patel; Georgios Nteliopoulos; Zacharoula Nikolakopoulou; Amanda Jackson; Myrtle Y. Gordon


Book ID
108677033
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
205 KB
Volume
152
Category
Article
ISSN
0007-1048

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## Abstract Chronic myeloid leukemia (CML) arises as a consequence of the expression of a chimeric fusion protein, p210BCRโ€ABL1, which is localized to the cytoplasm and has constitutive protein tyrosine kinase activity. Extensive publications report that p210BCRโ€ABL1 complexed with multiple cytopla