Antibodies to the E2 Protein of GB Virus C/Hepatitis G Virus: Prevalence and Risk Factors in Different Populations in Italy
β Scribed by P. Villari; G. Ribera; C.G.A. Nobile; I. Torre; G. Ricciardi
- Book ID
- 107704971
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 107 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0300-8126
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GB virus-C/hepatitis G virus (GBV-C/HGV) is an RNA virus that can be transmitted by transfusion with the diagnosis based on the detection of serum GBV-C/HGV RNA by reverse transcriptionpolymerase chain reaction. In order to evaluate the role of antibodies to the E2 protein (anti-E2) of GBV-C/HGV in
The prevalence of the new flavivirus GB virus C/hepatitis virus G (GBV-C/HGV) in different German populations was investigated by detection of viral genomes and anti-E2 antibodies. While blood donors had an overall prevalence of 10.4% there were increased rates for hemophiliacs (54.7%), hemodialysis
Sera from 483 patients at high (group 1, n = 313) and lower (group 2, n = 170) risk for exposure to hepatitis C were tested for antibodies to hepatitis C using first-generation (c100-3) and second-generation enzyme-linked immunosorbent assays and four-antigen recombinant immunoblot assay. The second