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Antibodies to retroviral proteins in autoimmune connective tissue disease. Relation to clinical manifestations and ribonucleoprotein autoantibodies

✍ Scribed by Annamari Ranki; Pekka Kurki; Senja Riepponen; Eija Stephansson


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
903 KB
Volume
35
Category
Article
ISSN
0004-3591

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## Abstract ## Objective T cell intracytoplasmic antigen 1 (TIA‐1) and TIA‐1–related protein (TIAR) are involved in posttranscriptional regulation of the expression of tumor necrosis factor α (TNFα) and other proteins. Given the pivotal role of TNFα in chronic inflammatory diseases, this study was