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Antibodies to P2 and P1 myelin antigens in experimental allergic neuritis and allergic encephalomyelitis

โœ Scribed by Burton Zweiman; Anne R. Moskovitz; Abdolmohammad Rostami; Robert P. Lisak; David E. Pleasure; Mark J. Brown


Book ID
119106516
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
371 KB
Volume
2
Category
Article
ISSN
0165-5728

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We examined the evolution of demyelination in spinal roots of Lewis rats immunized with whole nerve and complete Freund's adjuvant. Roots were morphologically normal until 11 days after immunization, when we found endoneurial edema and myelin vesiculation in the absence of mononuclear cell contacts.