Antibodies to HTLV-I in Nigerian blood-donors, their relatives and patients with leukaemias, lymphomas and other diseases

✍ Scribed by A. F. Fleming; R. Maharajah; M. Abraham; A. G. Kulkarni; S. R. Bhusnurmath; R. A. Okpara; Eka Williams; I. Akinsete; J. Schneider; H. Bayer; G. Hunsmann

• Publisher: John Wiley and Sons
• Year: 1986
• Tongue: French
• Weight: 582 KB
• Volume: 38
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910380605

✦ Synopsis

Antibodies to HTLV-I have been detected in sera from 15 (2.0%) of 736 adult blood-donors in Nigeria, in 4 (20.0%) of 20 patients with chronic lymphatic leukaemia, 3 (10.0%) of 30 with non-Hodgkin's lymphoma, one of I2 with Burkitt's lymphoma and one of 7 with acute lymphoblastic leukaemia. The frequency of positivity was higher (3.6%) in the blood-donors from the guinea and wooded savanna of northern Nigeria than in those from the rain-forest and mangrove swamps of southern Nigeria (1.8% in Lagos and 0.7"/0 in Calabar). Two of the 3 seropositive patients with lymphoma had clinical presentation and courses similar to those of Japanese and Caribbean patients with adult T-cell leukaemidlymphoma.

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