𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antibodies: from genes to targeted cancer gene therapy

✍ Scribed by Hawkins, R E; Whittington, H A; Watkins, S J; Gilham, D E

Book ID
110038331
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
57 KB
Volume
5
Category
Article
ISSN
0969-7128

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Antibody targeted gene transfer to endot
Antibody targeted gene transfer to endothelium
✍ P. H. Tan; M. Manunta; N. Ardjomand; S. A. Xue; D. F. P. Larkin; D. O. Haskard; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 343 KB

## Abstract ## Background One of the drawbacks of the currently available vectors for gene therapy is the lack of selectivity in gene delivery. We have therefore investigated a strategy to generate immunoliposomes to target non‐viral vectors to cell surface receptors on endothelium. ## Materials

Gene targeting: Roadmap to future therap
Gene targeting: Roadmap to future therapies
✍ Lars C. Huber; Thomas Pap; Ulf MΓΌller-Ladner; Renate E. Gay; Steffen Gay πŸ“‚ Article πŸ“… 2004 πŸ› Springer 🌐 English βš– 166 KB
Gene therapy targeting to tumor endothel
Gene therapy targeting to tumor endothelium
✍ Bazan-Peregrino, M; Seymour, L W; Harris, A L πŸ“‚ Article πŸ“… 2006 πŸ› Nature Publishing Group 🌐 English βš– 225 KB
Pharmacological aspects of targeting can
Pharmacological aspects of targeting cancer gene therapy to endothelial cells
✍ H.H. Sedlacek πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 350 KB

Targeting cancer gene therapy to endothelial cells seems to be a rational approach, because (a) a clear correlation exists between proliferation of tumor vessels and tumor growth and malignancy, (b) differences of cell membrane structures between tumor endothelial cells and normal endothelial cells