Antibodies against the large subunit of the EBV-encoded ribonucleotide reductase in patients with nasopharyngeal carcinoma
✍ Scribed by Michelle Ginsburg
- Book ID
- 102865334
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 818 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0020-7136
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In an attempt to clone and express proteins from the Epstein-Barr virus (EBV) cDNA library to be used as antigens in an enzyme-linked immunosorbent assay (ELISA) format to test against the antibodies found in the sera of nasopharyngeal carcinoma (NPC) patients, we have isolated and characterized thr
## Abstract Antibody titres to EBV‐associated antigens in Chinese NPC patients were analysed according to length of survival after diagnosis and to disease stage. Geometric mean titres of ADLC antibody were highest in the long‐term survivors, whereas VCA, EA and EBNA antibody titres showed an inver
## Abstract Ninety‐five sera from Chinese NPC patients in different stages of the disease, 38 sera from Chinese patients with other cancers, and 50 normal Chinese sera, were titrated for EBNA, VCA, EA and complement‐fixing (CF/S) EBV‐specific antibodies. The geometric mean (GMT) EBNA antibody titre
## Abstract Comparisons were made between 151 sera from 131 donors with Burkitt's lymphoma, nasopharyngeal carcinoma and other tumors of the head and neck area, from patients having had infectious mononucleosis and from healthy controls, in three EBV‐associated serological tests: intracellular immu