Antibodies against 60-kDa Heat-Shock Proteins in Human Immunodeficiency Virus Infection
✍ Scribed by ZOLTÁN PROHÁSZKA; DÉNES BÁNHEGYI; ESZTER UJHELYI; ISTVÁN KARÁDI; GEORGE FÜST
- Book ID
- 111393738
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 97 KB
- Volume
- 851
- Category
- Article
- ISSN
- 0890-6564
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Heat shock proteins (hsps) and cyclophilins (CypA) are intracellular chaperone molecules that facilitate protein folding and assembly. These proteins are selectively expressed in cells following exposure to a range of stress stimuli, including viral infection. Hsp species are highly immunogenic, eli
## Abstract Heat shock proteins (Hsp), especially 70 kDa heat shock protein (Hsp70) play an important role in the life cycle of HIV‐1 virus. Hsp70 is overexpressed in HIV‐infected cells and this is the most abundant Hsp associated with HIV virions. The aim of our study was to investigate whether HI