𝔖 Bobbio Scriptorium
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ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation

✍ Scribed by Yonath, Ada


Book ID
121420475
Publisher
Annual Reviews
Year
2005
Tongue
English
Weight
770 KB
Volume
74
Category
Article
ISSN
0066-4154

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## Abstract The glucopyranosyl moiety (ringβ€…I) of paromomycin was modified in a search for novel aminoglycoside antibiotics. The key intermediates were the 4β€²,6′‐__O__‐benzylidenated __N__‐Boc derivative **3** and the azido analogue **18**. The bromobenzoates **4** and **19** were prepared by treat