The plasma levels and tissue penetration of pefloxacin were studied after prophylactic administration to patients undergoing elective biliary surgery. Pefloxacin was administered as a single dose of 800 mg given intravenously as an infusion 1 h before surgery. Over a period of two years, cultures of
β¦ LIBER β¦
Antibiotics in biliary surgery
β Scribed by A. A. Gunn
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 330 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0007-1323
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β¦ Synopsis
Abstract
Infection is the major cause of morbidity following biliary surgery and it has been shown that the patients with infected bile can be detected preoperatively. This paper presents the results of a controlled trial comparing patients expected to have infected bile who received surgical treatment with and without antibiotic therapy. The results showed a reduction in the incidence and severity of complications in the treated group.
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