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Antibiotics from Gliding Bacteria, LXXIII Indole and Quinoline Derivatives as Metabolites of Tryptophan in Myxobacteria

✍ Scribed by Böhlendorf, Bettina ;Bedorf, Norbert ;Jansen, Rolf ;Trowitzsch-Kienast, Wolfram ;Höfle, Gerhard ;Forche, Edgar ;Gerth, Klaus ;Irschik, Herbert ;Kunze, Brigitte ;Reichenbach, Hans


Book ID
102904241
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
524 KB
Volume
1996
Category
Article
ISSN
0947-3440

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✦ Synopsis


Abstract

Two groups of 3‐substituted indole 1, 6–9 as well as 4‐substituted quinoline derivatives 2–5 and harman (10) were isolated from various species and genera of myxobacteria. They were identified by their spectroscopic data. Some of the metabolites show moderate antifungal activity. Their biosynthetic origin in myxobacteria was demonstrated for 1, 2, and 3 by incorporation of L‐[1'‐^14^C]tryptophan.