Antibacterial and swelling properties of N-isopropyl acrylamide grafted and collagen/chitosan-immobilized polypropylene nonwoven fabrics

✍ Scribed by Chyung-Chyung Wang; Wen-Yean Wu; Cheng-Chi Chen

• Book ID: 102300202
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 228 KB
• Volume: 96B
• Category: Article
• ISSN: 1552-4973
• DOI: 10.1002/jbm.b.31709

✦ Synopsis

Abstract

The different molar ratios of collagen/chitosan were used to be immobilized on polypropylene nonwoven fabrics grafted with N‐isopropyl acrylamide (abbr. PP‐g‐NIPAAm‐i‐Col/Chi). For a controlled immobilizing time and NIPAAm concentration, the collagen/chitosan immobilized values and the antibacterial properties of PP‐g‐NIPAAm‐i‐Col/Chi increased with increasing amount of chitosan in the mixture of collagen/chitosan. The crosslinking reaction between the grafted polyNIPAAm and collagen/chitosan molecules was clearly confirmed by the examination of the spectra of the surface reflection infrared spectroscopy (IR). The values of water absorption and water diffusion coefficient of PP‐g‐NIPAAm‐i‐Col/Chi decreased with increase of the chitosan in the mixture of collagen/chitosan and the value of immobilized collagen/chitosan at the same pH value of buffering water. The PP‐g‐NIPAAm‐i‐Col/Chi have excellent water absorption, water permeability, and antibacterial properties and would be suitable for the healing of wounded skin area. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2011.