Antibacterial and antifungal activities of several populations of Tunisian Citrullus colocynthis Schrad. immature fruits and seeds

✍ Scribed by B. Marzouk; Z. Marzouk; R. Décor; L. Mhadhebi; N. Fenina; M. Aouni

• Book ID: 103846983
• Publisher: Masson Editeur
• Year: 2010
• Tongue: French
• Weight: 263 KB
• Volume: 20
• Category: Article
• ISSN: 1156-5233
• DOI: 10.1016/j.mycmed.2010.05.006

✦ Synopsis

Objective. -Skin infections and gynaecological and pulmonary problems produced by microorganisms are widespread in the entire globe. The treatment of these infections is mainly based on the use of synthetic drugs, many of which have lost their effectiveness, in recent years, due to the development of resistant strains, and to the rise of opportunistic fungal infections. The aim of this study was to assess in vitro antibacterial and anticandidal activity of aqueous immature fruit and seed extracts, screened for the alkaloid and flavonoid levels, of seven populations of Citrullus colocynthis Schrad. Material and method. -C. colocynthis Schrad. samples were harvested and their identification verified. Aqueous extracts (from immature fruits and seeds) were screened for activity against Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Enterococcus faecalis and Staphylococcus aureus) bacteria -and four Candida spp. (Candida glabrata, Candida albicans, Candida parapsilosis and Candida krusei). Microdilution method was used to investigate the antimicrobial activity.