Antibacterial activity of Orobanche cernua extract

✍ Scribed by Ismail Saadoun; Khalid M. Hameed

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 161 KB
• Volume: 39
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/(sici)1521-4028(199912)39:5/6<377::aid-jobm377>3.0.co;2-0

✦ Synopsis

The effect of the parasitic plant Orobanche cernua extract was evaluated on 5 different Grampositive and Gram-negative bacteria. Dilution experiments show that the minimum inhibitory concentration (MIC; Pg/ml) of the extract was as follows: Staphylococcus aureus -1526.5; Streptococcus sp. -3125; Streptococcus pyogenes -25000 and both for Bacillus cereus and Escherichia coli-50 000 Pg/ml. Data indicated that the MIC of 3125 Pg/ml is equal to cefotaxime (30 Pg) and tobromycin (10 Pg) activity against Streptococcus sp. and S. aureus, respectively; 25 000 and 50 000 Pg/ml is equal to cefotaxime (30 Pg) activity against S. pyogenes and B. cereus, respectively, and 50 000 Pg/ml is equal to nalidixic acid (30 Pg) activity against E. coli. It can be concluded that the O. cernua extract displays remarkable activity against some Gram-positive bacteria such as Streptococcus and Staphylococcus.