Structure–activity relationship studies
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Marcos A. Fázio; Vani X. Oliveira Jr.; Philippe Bulet; M. Terêsa M. Miranda; Sir
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Article
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2006
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Wiley (John Wiley & Sons)
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English
⚖ 559 KB
## Abstract Gomesin is an antimicrobial peptide isolated from hemocytes of the Brazilian spider __Acanthoscurria gomesiana__ that contains two disulfide bridges Cys^2‐15^/Cys^6‐11^ and presents a β‐hairpin structure. To investigate the role of the disulfide bridges on gomesin conformation, bioactiv