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Antiangiogenesis in swine ovarian follicle: A potential role for 2-methoxyestradiol

✍ Scribed by Giuseppina Basini; Simona Bussolati; Sujen Eleonora Santini; Federica Bianchi; Maria Careri; Alessandro Mangia; Marilena Musci; Francesca Grasselli

Book ID
116892061
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
321 KB
Volume
72
Category
Article
ISSN
0039-128X

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## Abstract In the current study, we investigated the mechanism relating downregulation of mitogen‐activated protein kinase kinase 4 (MKK4) expression to development of ovarian cancer. Over‐expression of the MKK4 gene in TOV‐21 G cells, a line with homozygous deletion of MKK4, resulted in morpholog