Antiaggregant effects on human platelets of culinary herbs
โ Scribed by Kenji Okazaki; Shigenori Nakayama; Kazuyoshi Kawazoe; Yoshihisa Takaishi
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 58 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
โฆ Synopsis
The inhibitory effects of methanol extracts of 20 herb species on human platelet aggregation were investigated. Allspice, basil, marjoram, tarragon and thyme strongly inhibited the platelet aggregation induced by collagen. Basil, marjoram and tarragon strongly inhibited platelet aggregation induced by ADP. An active compound, arbutin, was isolated from sweet marjoram as an inhibitor of platelet aggregation induced by collagen; ADP, arachidonic acid (AA) and thrombin.
๐ SIMILAR VOLUMES
Because the deposition of beta-amyloid protein (Abeta) is a consistent pathological hallmark of Alzheimer's disease (AD) brains, inhibition of Abeta generation, prevention of Abeta fibril formation, or destabilization of preformed Abeta fibrils would be attractive therapeutic strategies for the trea