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Anti-tumour effects of nobiletin, a citrus flavonoid, on gastric cancer include: antiproliferative effects, induction of apoptosis and cell cycle deregulation

✍ Scribed by N. Yoshimizu; Y. Otani; Y. Saikawa; T. Kubota; M. Yoshida; T. Furukawa; K. Kumai; K. Kameyama; M. Fujii; M. Yano; T. Sato; A. Ito; M. Kitajima

Book ID: 108603700
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 263 KB
Volume: 20
Category: Article
ISSN: 0269-2813
DOI: 10.1111/j.1365-2036.2004.02082.x

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The ability of lonidamine (LND), an energolytic derivative of indazole-carboxylic acid, to modulate the cytotoxicity of Taxol (TX) was investigated in the A2780 human ovarian cancer cell line. Different cytotoxicity results were obtained as a function of treatment schedule. Specifically, TX followed