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Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model

✍ Scribed by Monica Rinaldi; Daniela Fioretti; Sandra Iurescia; Emanuela Signori; Pasquale Pierimarchi; Davide Seripa; Giancarlo Tonon; Vito Michele Fazio

Book ID: 116296616
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 457 KB
Volume: 370
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2008.03.076

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## Abstract The costimulatory molecule, B7‐2, is expressed by various lymphomas, but this level of expression is not sufficient to generate effective anti‐tumor immunity __in vivo__. To determine whether up‐regulated expression of the costimulatory molecule, B7‐2, leads to more effective anti‐tumor