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Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model

✍ Scribed by Tullia C. Bruno; Cristin Rothwell; Joseph F. Grosso; Derese Getnet; Hung Rong Yen; Nicholas M. Durham; George Netto; Drew M. Pardoll; Charles G. Drake

Book ID: 112179533
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 634 KB
Volume: 72
Category: Article
ISSN: 0270-4137
DOI: 10.1002/pros.21453

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## Abstract To identify tumor‐associated antigens as putative targets for developing immunotherapies against prostate cancer, we investigated the ability of T cells derived from the peripheral blood lymphocytes of prostate cancer patients to recognize autologous tumor cells. The technical challenge