𝔖 Bobbio Scriptorium
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Anti-TNFα therapy modulates the IL-33/ST2 axis in inflammatory bowel disease

Book ID
116399217
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
47 KB
Volume
48
Category
Article
ISSN
1043-4666

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Characterization of the novel ST2/IL-33
Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease
✍ Caroll J. Beltrán; Lucía E. Núñez; David Díaz-Jiménez; Nancy Farfan; Enzo Candia 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 671 KB

## Background: St2 has been proposed to be a regulator of inflammation and th1/th2 balance. st2l is the il-33 membrane receptor and belongs to the il-1r family. the soluble variant, st2s, is identical to the extracellular region of st2l and competes for il-33 binding, inhibiting receptor signaling.