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Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo

✍ Scribed by J. E. Bluff; M. Amarzguioui; J. Slattery; M. W. R. Reed; N. J. Brown; C. A. Staton

Publisher: Springer US
Year: 2010
Tongue: English
Weight: 627 KB
Volume: 128
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-010-1149-8

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## Abstract Thromboembolic complications are frequently associated with advanced cancer. Interestingly, one of the major initiators of blood coagulation, tissue factor (TF), is reported to be overexpressed in several tumor types and can be found on both tumor cells and tumor vasculature. Although t