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Anti-T cell receptor antibody treatment of rats with established autologous collagen-induced arthritis: suppression of arthritis without reduction of anti-type II collagen autoantibody levels

✍ Scribed by Tom J. Goldschmidt; Rikard Holmdahl


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
441 KB
Volume
21
Category
Article
ISSN
0014-2980

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Treatment of collagen-induced arthritis
✍ Kexing Fan; Jianxin Dai; Hao Wang; Huafeng Wei; Zhiguo Cao; Sheng Hou; Weizhu Qi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 690 KB

## Abstract ## Objective To test the effects of a novel monoclonal antibody (mAb) against human osteopontin (OPN) in the prevention and treatment of collagen‐induced arthritis (CIA) and to elucidate the underlying mechanisms of these effects. ## Methods DBA/1J mice immunized with type II collage