Anti-sickling potential of Aloe vera extract

Column selection and method development

Column selection and method development for the separation of nucleoside phosphotriester diastereoisomers, new potential anti-viral drugs. Application to cellular extract analysis

✍ J. F. Goossens; C. Foulon; A.-L. Villard; J.-Y. Puy; I. Lefebvre; C. Perigaud; C 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 261 KB

## Abstract Analytical HPLC methods using derivatized cellulose and amylose chiral stationary phases used in normal and reversed‐phase modes were developed for the diastereoisomeric separation of mononucleotide prodrugs (pronucleotides) of 3′‐azido‐2′,3′‐dideoxythymidine (AZT). The resolutions were