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Anti-proliferative effects of protein kinase C inhibitors in human keratinocytes

✍ Scribed by Hegemann, Lutz; Bonnekoh, Bernd; van Rooijen, Lucio A.A.; Mahrle, Gustav


Book ID
123565103
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
719 KB
Volume
4
Category
Article
ISSN
0923-1811

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The protein-kinase-C (PKC) family of iso-enzymes regulates mitogenic signal transduction in colorectal-cell lines. Its function in human colonic mucosal proliferation is controversial. Our study investigated the role of PKC with regard to proliferation and changes of PKC iso-enzyme expression in col