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Anti-proliferative activity of hydnocarpin, a natural lignan, is associated with the suppression of Wnt/β-catenin signaling pathway in colon cancer cells

✍ Scribed by Lee, Min-Ai; Kim, Won Kyung; Park, Hyen Joo; Kang, Sam Sik; Lee, Sang Kook


Book ID
121740767
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
742 KB
Volume
23
Category
Article
ISSN
0960-894X

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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi