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Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells. Int. J. Cancer,72, 844–850 (1997)

✍ Scribed by M. Distefano; G. Scambia; C. Ferlini; C. Gaggini; R. De Vincenzo; A. Riva; E. Bombardelli; I. Ojima; A. Fattorossi; P. Benedetti Panici; S. Mancuso

Publisher: John Wiley and Sons
Year: 1998
Tongue: French
Weight: 46 KB
Volume: 76
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19980330)76:1<164::aid-ijc25>3.0.co;2-b

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Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells

✍ Mariagrazia Distefano; Giovanni Scambia; Cristiano Ferlini; Cristiana Gaggini; R 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 222 KB 👁 1 views

Paclitaxel, docetaxel and a series of new analogs synthesized from 14␤-hydroxy-10-deacetylbaccatin III (14-OH-DAB), a natural diterpene closely related to the core synthon of the 2 above prototypes, were tested in vitro for their growth-inhibitory activity on different human cancer cell lines, inclu