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Anti-p40 Antibodies Ustekinumab and Briakinumab: Blockade of Interleukin-12 and Interleukin-23 in the Treatment of Psoriasis

โœ Scribed by Mona Gandhi; Eihab Alwawi; Kenneth B. Gordon

Book ID
116879468
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
282 KB
Volume
29
Category
Article
ISSN
1085-5629

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โœ Pauline L. Martin; Clifford Sachs; Noritaka Imai; Hideshi Tsusaki; Satoru Oneda; ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 544 KB

## Abstract **BACKGROUND:** Ustekinumab is a human monoclonal antibody that binds to the p40 subunit of interleukin (IL) 12 and ILโ€23 and inhibits their pharmacological activity. To evaluate potential effects of ustekinumab treatment during pregnancy, developmental studies were conducted in cynomol