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Anti-oxidative effect of Klotho on endothelial cells through cAMP activation

✍ Scribed by Hiromi Rakugi; Naomichi Matsukawa; Kazuhiko Ishikawa; Jin Yang; Michio Imai; Masashi Ikushima; Yoshihiro Maekawa; Iwao Kida; Jun-ichi Miyazaki; Toshio Ogihara


Book ID
107571077
Publisher
Springer
Year
2007
Tongue
English
Weight
294 KB
Volume
31
Category
Article
ISSN
0969-711X

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## Background: Oxidized low-density lipoprotein (oxldl) exerts proliferation and apoptosis in vascular cells, depending on its concentration and the exposure time. various steps in the cell cycle and in the apoptotic signaling cascade are modulated by o2-, and oxldl stimulates vascular o2- formatio