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Anti-oncogene Product p53 Binds DNA Helicase

✍ Scribed by Takeshi Sakurai; Motoshi Suzuki; Tetsuya Sawazaki; Shunsuke Ishii; Shonen Yoshida

Book ID
115601875
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
591 KB
Volume
215
Category
Article
ISSN
0014-4827

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The tumor suppressor p53 i s a multifunctional protein whose main duty is to preserve the integrety of the genome. This function of wild-type p53 as "guardian of the genome" is achieved at different levels, as a cell cycle checkpoint protein, halting the cell cycle upon DNA damage, and via a direct