Anti-neuraminidase antibodies: Which substrate should be used to test their effect on influenza virus neuraminidase

Analysis of the Binding of the Fab Fragm

Analysis of the Binding of the Fab Fragment of Monoclonal Antibody NC10 to Influenza Virus N9 Neuraminidase from Tern and Whale Using the BIAcore Biosensor: Effect of Immobilization Level and Flow Rate on Kinetic Analysis

✍ Alexander A. Kortt; Edouard Nice; L.Clem Gruen 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 121 KB

The binding of the Fab fragment of monoclonal antibody NC10 to influenza virus N9 neuraminidase, isolated from tern and whale, was measured using an optical biosensor. Both neuraminidases, homotetramers of 190 kDa, were immobilized to avoid multivalent binding, and the binding of the monovalent NC10