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Anti-Microbial Activity and Film Characterization of Thiazolidinone Derivatives of Chitosan

โœ Scribed by Anandrao R. Kulkarni; Venktrao H. Kulkarni; Jathi Keshavayya; Vijaykumar I. Hukkeri; Hsing-Wen Sung

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
69 KB
Volume
5
Category
Article
ISSN
1616-5187

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โœฆ Synopsis

Abstract

Communication: Thiazolidinone derivatives (TDCs) were prepared by converting chitosan into chitosan's Schiff's bases (CSBs), followed by treatment with mercaptoacetic acid. Both CSBs and TDCs were tested for antimicrobial activity against four different bacteria. All TDCs showed comparatively better antiโ€microbial activity without much affecting basic physical properties of chitosan such as filmโ€forming capacity, tensile strength, etc. This indicates that chitosan derivatives with a thiazolidinone moiety might be a better material for wound dressing.
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