Anti-MHC Class II Alpha Chain Antibodies Block Staphylococcal Enterotoxin B Induced T-cell Proliferation

Peptide-antibody conjugates for tumour t

Peptide-antibody conjugates for tumour therapy: A MHC-class-II-restricted tetanus toxin peptide coupled to an anti-IG light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells

✍ Zhiwei Yu; Frank Healy; Danila Valmori; Patricia Escobar; Giampietro Corradin; J 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 729 KB

Anti-idiotype antibody therapy of B-cell lymphomas, despite numerous promising experimental and clinical studies, has so far met with limited success. Tailor-made monoclonal antiidiotype antibodies have been injected into a large series of lymphoma patients, with a few impressive complete tumour rem