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Anti-metastatic potential of human Vδ1+γδ T cells in an orthotopic mouse xenograft model of colon carcinoma

✍ Scribed by Christel Devaud, Benoît Rousseau, Sonia Netzer…


Book ID
120771037
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
710 KB
Volume
62
Category
Article
ISSN
0340-7004

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Peripheral gammadelta T cells derived from healthy donors were found to exhibit cytotoxicity against a variety of tumor cell lines in vitro, including CNE2, which was established from nasopharyngeal carcinoma (NPC). The anti-tumor effects were further studied in a mouse model. Control nude mice inoc