๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Anti-leukemic potential of methyl-cobalamin inactivation by nitrous oxide

โœ Scribed by Dr. J. Abels; A. C. M. Kroes; A. A. M. Ermens; J. Van Kapel; M. Schoester; L. J. M. Spijkers; J. Lindemans


Book ID
101433972
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
434 KB
Volume
34
Category
Article
ISSN
0361-8609

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Enhanced therapeutic effect of methotrex
โœ A. C. M. Kroes; J. Lindemans; M. Schoester; J. Abels ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 785 KB

Exposure to nitrous oxide interferes selectively with the coenzyme function of vitamin B12 and causes inactivation of methionine synthetase, with subsequent impairment of folate metabolism and reduction of cellular proliferation. In a rat leukemia model (BNML) we investigated the combined administra