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Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

✍ Scribed by R.G. Knowles; M. Salter; S.L. Brooks; S. Moncada


Book ID
115763373
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
401 KB
Volume
172
Category
Article
ISSN
0006-291X

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Liver and lung metallothionein (MT) levels were increased by endotoxin. The administration of superoxide dismutase (SOD) or allopurinol (ALLO) before (30-60 min) or after (24-32 h) the endotoxin treatment either increased or did not affect the effect of endotoxin on MT levels, depending on the parti