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Anti-inflammatory Effects of Prostaglandin E2 Receptor 4 Activation in Murine Cardiac Transplantation

โœ Scribed by Jun-Ichi Suzuki; Mitsuaki Isobe

Book ID
116338045
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
44 KB
Volume
13
Category
Article
ISSN
1532-8414

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Cyclooxygenase (COX) converts arachidonic acid to prostaglandin (PG) H 2 , which is further metabolized to various prostaglandins, prostacyclin and thromboxane A 2 . COX exists in at least two different isoforms. COX-1 is constitutively expressed, whereas COX-2 is induced by proinflammatory stimuli.