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Anti-inflammatory Effect of α-Linolenic Acid and Its Mode of Action through the Inhibition of Nitric Oxide Production and Inducible Nitric Oxide Synthase Gene Expression via NF-κB and Mitogen-Activated Protein Kinase Pathways

✍ Scribed by Ren, Jie; Chung, Sung H.

Book ID
126834872
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
404 KB
Volume
55
Category
Article
ISSN
0021-8561

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## Abstract Cytokine‐induced expression of inducible nitric oxide synthase (iNOS) and concomitant production of nitric oxide (NO) involve activation of mitogen‐activated protein (MAP) kinases and are in most cases mediated by the transcription factor NF‐κB. We investigated the role of p38 MAP kinas