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Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-κB pathway

✍ Scribed by Debjani Sarkar; Piu Saha; Sunita Gamre; Surajit Bhattacharjee; Chellaram Hariharan; Sudipto Ganguly; Rupashree Sen; Goutam Mandal; Subrata Chattopadhyay; Subrata Majumdar; Mitali Chatterjee

Book ID
116576379
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
545 KB
Volume
8
Category
Article
ISSN
1567-5769

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Pelubiprofen is a non-steroidal anti-inflammatory drugs (NSAIDs) that is related both structurally and pharmacologically to ibuprofen. Antiinflammatory properties of ibuprofen are due to its ability to both decrease prostaglandin synthesis by inhibiting the activities of cyclooxygenases (COXs) and I