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Anti-inflammatory effect of 1α,25-dihydroxyvitamin D3 in human coronary arterial endothelial cells: Implication for the treatment of Kawasaki disease

✍ Scribed by Yasuo Suzuki; Takashi Ichiyama; Ayami Ohsaki; Shunji Hasegawa; Masahiro Shiraishi; Susumu Furukawa

Book ID: 116698275
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 311 KB
Volume: 113
Category: Article
ISSN: 0960-0760
DOI: 10.1016/j.jsbmb.2008.12.004

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The hormone I ,25-dihydroxyvitamin D3 (VD) has a potential use as an anti-tumor agent, but its clinical applications are restricted by its strong calcemic activity. This has led to the development of VD analogues with selectively increased growthinhibitory activity. One of the most potent analogues