Screening and Toxicity of Anti-Inflammatory Drugs.- 19 Screening and Assessment of the Potency of Anti-Inflammatory Drugs in vitro.- A. Introduction.- B. Interaction With Non-Enzymic Proteins.- I. Binding to Plasma Proteins.- 1. Displacement Reactions.- 2. Disulphide Interchange Reactions.- 3. Prote
Anti-Inflammatory Drugs in Asthma
β Scribed by James L. Lordan, Ratko DjukanoviΔ (auth.), Dr. Anthony P. Sampson, Prof. Martin K. Church (eds.)
- Publisher
- BirkhΓ€user Basel
- Year
- 1999
- Tongue
- English
- Leaves
- 275
- Series
- Progress in Inflammation Research
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
For some years, international guidelines on the management of asthma have stressed the importance of early intervention with anti-inflammatory drugs to prevent acute asthma exacerbations and to avert chronic inflammatory damage to the airway. Introduced by a broad survey of the targets for anti-inflammatory drugs, this book proceeds to bring together the most recent research into the mechanisms and clinical benefits of presently available anti-inflammatory treatments including corticosteroids, cromones, and theophylline. For the first time, these drugs are discussed alongside the newly introduced leukotriene modifier drugs, and in the context of frontline research into anti-inflammatory drugs of the future. Leading authorities in their fields evaluate the prospects of novel anti-IgE agents and cytokine antagonists, and examine recent developments in immunosuppressant compounds, protease inhibitors, and selective phosphodiesterase inhibitors. This book is an up-to-date and authoritative survey which will be invaluable to university and pharmaceutical company researchers working on anti-asthma and anti-allergy drugs and to respiratory physicians keeping abreast of developments in their specialty.
β¦ Table of Contents
Front Matter....Pages i-viii
Anti-Inflammatory Drugs in Asthma: The Pathophysiology of Asthma....Pages 1-33
Corticosteroids....Pages 35-85
Phosphodiesterases in Asthma....Pages 87-135
Ξ² 2 -Agonists....Pages 137-151
Mast Cell Stabilizing Drugs....Pages 153-167
Anti-Leukotriene Therapy for Asthma....Pages 169-197
Immunomodulators....Pages 199-214
Anti-IgE Agents....Pages 215-227
Mast Cell Proteases as New Targets for Therapeutic Intervention in Asthma....Pages 229-249
Cytokine and Adhesion Molecule Antagonists....Pages 251-272
Back Matter....Pages 273-276
β¦ Subjects
Medicine/Public Health, general
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