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Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain

✍ Scribed by Hiroshi Shigetomi; Akira Onogi; Hirotaka Kajiwara; Shozo Yoshida; Naoto Furukawa; Shoji Haruta; Yasuhito Tanase; Seiji Kanayama; Taketoshi Noguchi; Yoshihiko Yamada; Hidekazu Oi; Hiroshi Kobayashi


Publisher
SP Birkhäuser Verlag Basel
Year
2010
Tongue
English
Weight
355 KB
Volume
59
Category
Article
ISSN
1420-908X

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## Abstract Soman‐poisoned rats display cholinergic crisis, a systemic mast cell degranulation characteristic of anaphylactic reactions and an excitotoxin‐like sequential seizure and neuronal degeneration. The protection of guinea pigs from soman lethality by prophylactic administration of the seri