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Anti-IL-17A Autovaccination Prevents Clinical and Histological Manifestations of Experimental Autoimmune Encephalomyelitis

✍ Scribed by CATHERINE UYTTENHOVE; CAROLINE SOMMEREYNS; IVAN THÉATE; THOMAS MICHIELS; JACQUES VAN SNICK


Book ID
111484257
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
129 KB
Volume
1110
Category
Article
ISSN
0890-6564

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Development of an anti-IL-17A auto-vacci
✍ Catherine Uyttenhove; Jacques Van Snick 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

## Abstract IL‐17 has been associated with multiple inflammatory disorders such as rheumatoid arthritis, asthma and multiple sclerosis. As these diseases require long‐term treatment we turned to an auto‐vaccine strategy for IL‐17 neutralization __in vivo__. Mouse IL‐17A was covalently linked to ova